Structural basis of ligand activation and inhibition in a mammalian TRPV4 ion channel 2023-10-26
An analytical framework for decoding cell type-specific genetic variation of gene regulation 2023-10-26
UBE2M-mediated neddylation of TRIM21 regulates obesity-induced inflammation and metabolic disorders 2023-10-26
MIRO-1 interacts with VDAC-1 to regulate mitochondrial membrane potential in Caenorhabditis elegans 2023-10-26
Myofiber Baf60c controls muscle regeneration by modulating Dkk3-mediated paracrine signaling 2023-10-26
Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae 2023-10-26
USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities 2023-10-26
Triggered Golgi membrane enrichment promotes PtdIns(4,5)P2 generation for plasma membrane repair 2023-10-26
Nodal coordinates the anterior-posterior patterning of germ layers and induces head formation in zebrafish explants 2023-10-26
AMLnet, A deep-learning pipeline for the differential diagnosis of acute myeloid leukemia from bone marrow smears 2023-10-26
Urease of Aspergillus fumigatus is required for survival in macrophages and virulence 2023-10-26
An integrative profiling of metabolome and transcriptome in the plasma and skeletal muscle following an exercise intervention in diet-induced obese mice 2023-10-26
Unsaturated bond recognition leads to biased signal in a fatty acid receptor 2023-10-26
Histamine H2 receptor deficit in glutamatergic neurons contributes to the pathogenesis of schizophrenia 2023-10-26
MAPK4 silencing in gastric cancer drives liver metastasis by positive feedback between cancer cells and macrophages 2023-10-26
Epithelial Gab1 calibrates RIPK3-dependent necroptosis to prevent intestinal inflammation 2023-10-26
Influenza-trained mucosal-resident alveolar macrophages confer long-term antitumor immunity in the lungs 2023-10-26
FXYD3 enhances IL-17A signaling to promote psoriasis by competitively binding TRAF3 in keratinocytes 2023-10-26
The opportunistic pathogen Pseudomonas aeruginosa exploits bacterial biotin synthesis pathway to benefit its infectivity 2023-10-26
Type I interferon/STAT1 signaling regulates UBE2M-mediated antiviral innate immunity in a negative feedback manner 2023-10-26